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Нажимая кнопку "Продолжить", я принимаю политику конфиденциальности

1. When the white mouse infected with E. coli was intraperitoneally revealed: a pronounced vascular pattern, hemorrhages in the liver, heart, adrenal glands, lungs, peritonitis, abscesses in the liver. When sowing smears-prints of the liver, spleen, blood, an E. coli is isolated. Justify the forms of infection in the experimental animal.

2. When sowing the internal organs of a white mouse that died after intraperitoneal infection with Staphylococcus aureus, multiple lesions of staphylococcus internal organs (abscesses) were revealed. What are the properties of staphylococcus associated purulent processes of internal organs of the white mouse?

3. On the blood agar, the studied staphylococcus culture gave a hemolysis zone around the colonies, yellow-salt agar around the colonies - a rainbow rim, the ability to coagulate plasma was found. Justify the properties of the isolated culture of staphylococcus.

Tests:

11. Toxins that increase the permeability of the surface membrane of erythrocytes and leukocytes

A) membrane toxins

B) Functional blockers

C) exfoliates and erythrogens

D) cytotoxins

E) endotoxins

2. Anatoxin, differs from toxin

A) preservation of immunogenic and toxic properties

B) loss of immunogenic properties

C) loss of toxic properties

D) preservation of toxic properties

E) preservation of immunogenic and loss of toxic properties

3. Integrative infection, viremia, damage to cells of the immune system, formation of intracellular inclusions, is typical for

A) bacterial diseases

B) protozoal diseases

C) fungal diseases

D) bacterial and viral diseases

E) viral diseases

4. Infection accompanied by reproduction of viruses in host cells and the formation of new virions

A) autoinfection

B) persistent

C) productive

D) endogenous

E) exogenous

5. Infection resulting from the transfer of pathogens from one biotope to another

A) convalescence

B) autoinfection

C) endogenous infection

D) superinfection

E) exogenous infection

6. An infection in which microorganisms do not spread throughout the body

A) generalized

B) Monoinfection

C) superinfection

D) focal infection

E) a manifest infection

7. Infection, in which the pathogen spreads through the body

A) exogenous

B) generalized

C) autoinfection

D) reinfection

E) superinfection

8. Infection characterized by a prolonged stay of microorganisms in the macroorganism

A) latent infection

B) chronic infection

C) manifest infection

D) secondary infection

E) acute infection

9. Toxins affecting the process of interaction of cells with each other and with intercellular substances

A) membrane toxins

B) enterotoxins

C) cytotoxins

D) erythrogenins

E) Functional blockers

10. Form of infection in which germs and viruses spread hematogenously and do not reproduce in blood

A) Toxinemia

B) sepsis

C) Septicopaemia

D) toxic septic shock

E) bacteremia

Lesson№ 14.

1. Topic: Natural resistance of the macroorganism. Humoral and cellular factors of nonspecific immunity.

2. Aim: To master methods for determining nonspecific defense factors and methods for assessing the immunological status of a microorganism

3. Objectives: To teach methods of determining phagocytic indices and opsonophagocyte index. To characterize the humoral factors of natural immunity.

4. Main questions of the topic:

1. Formulate the concept of "immunity", the main functions of immunity.

2. Types of immunity.

3. Mechanisms of species immunity.

4. Humoral factors of nonspecific immunity. Lysozyme. Proteins of acute phase.

5. Cellular factors of nonspecific immunity. Natural killers.

6. Formulate the concept of "phagocytosis". Cells that belong to the phagocytes of their function.

7. List the main stages of phagocytosis.

8. Describe the differences between completed and incomplete phagocytosis, their consequences.

9. Representing and secretory functions of phagocytes.

10. Definition of phagocytic indices, opsonins and opsonization.

11. The complement system. Activation of the complement system.

12. Functions of the complement system.

13. The system of interferons.

14. The human immune system as a diffuse organ.

15. Cells of the immune system.

5. Methods of learning and teaching: дисскусия

6. Literature:

1. Medical microbiology, virologists and immunology. Ed. Academician of RAMS Zverev VV, Professor Boychenko MN - Moscow, GEOTAR-Media, 2010. - 1t. - 900 b.

2. Medical microbiology, virology and immunology. Ed. Vorobyeva A.A. - Moscow: MIA, 2008. - 690 p.

3. Medical microbiology, immunology and virology: a textbook for honey. universities. Ed. Korotyaeva AI, Babicheva SA - 5-еизд., Испр.и доп. - SPb .: SpecLit, 2012. - 760 pp. : ill.

4. Medical microbiology, virology, immunology. Ed. Borisova LB ..- M .: MIA, 2006.-734 p.

5. Medical Microbiology / Ch. Ed. Pokrovsky VI, Pozdeev O.K. - Moscow: GEOTAR MEDICINE, 2007.

6. Atlas on medical microbiology, virology and immunology: atlas / ed .: AS Bykov, AA Vorob'ev, VV Zverev. - 2 nd ed., Ext. - M .: Honey. inform. agency, 2008. - 272 p .: ill.

7. A guide to practical exercises on medical microbiology, virology and immunology. Ed. Tetz V.V. -М.: Медицина, 2002.-352 с.

8. Computer program "Diamorph" - "Medical microbiology" - atlas-guidance on bacteriology of mycology, protozoology and virology, edited by acad. prof. Vorobyeva A.A.

9. The determinant of bacteria Berdzhi / Ed. D. Houlta, N. Krig, P. Snitai et al., Moscow: Mir, 1997. - In 2 volumes.

In english language

25. Microbiology Fundamentals: A Clinical Approach - Standalone book 2nd Edition.

26. Richard V Georing, Hazel M Docrell, Mark Zukerman, Derek Wakelin, Ivan M Roit, Cedric Mims, Peter L Chiodini «Medical Microbiology», 4^th Edithion, 2008, UK, p.656.

27. Jacquelyn G Black «Microbiology», 7 th ,WILEY, 2010, p. 846.

28. Patric R Muray, Ken S Rosenthal, Michael F Pfaller «Medical Microbiology», 5th Edithion, 2008, p. 962.

Electronic resources:

1. Medicine 3 year [Electrones resource]: a course of lectures. - Electron. text dan. (24.0 MB). - M: Publishing house "Balance", 2005. -1 эл. opt. disk (CD-ROM).

2. Medical microbiology ATLAS - a guide to bacteriology, mycology, protozoology and virology [Electron resource]: for stud. and doctors / ed. A.S. Bykov. -M., 2001. -1 el. opt. disk (CD-ROM).

3. Workshop for laboratory studies on general microbiology [Electron resource]: teaching method. Manual / R.T. Dzhanabaev [et al.] -Sh., 2004. -1 e. opt. disk (CD-ROM).