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If a suspected acute respiratory infection from a patient with acute respiratory disease was prepared, a swab from the lower nasal shell was prepared. Fixing in acetone, treated with anti-influenza serum, then after rinsing it was filled with luminescent serum. What was the purpose of this study? Which microscope is used?

       Tests:

1. Antibodies that are unable to aggregate particles into conglomerates, connecting with an antigen

A) normal

B) abzymes

C) polyclonal

D) incomplete

E) monoclonal

2. In a pool of immunoglobulins synthesized by a set of cells after immunization with a mono-determinant antigen, antibodies

A) normal

B) incomplete

C) polyclonal

D) abzyme

E) monoclonal

3. Immunoglobulins found in serum and in secrets on the surface of the mucous membranes belong to the classes

A) Ig G

B) Ig A

C) IgM

D) Ig D

E) Ig E

4. Lymphocytes that block the development of humoral and cellular immunity

A) T-suppressors

B) T-helpers

C) T-killers

D) T-effectors

E) B-lymphocytes

5. Cytocidal cells that destroy target cells

A) T-helpers

B) T-killers

C) T-effectors

D) T-suppressors

E) B-lymphocytes

6. Common antigens that occur in different animal species

A) half-haptens

B) haptens

C) heteroantigens

D) propagens

E) alloantigens

7. Various antigens that occur within one species

A) proantigens

B) half-haptens

C) alloantigens

D) heteroantigens

E) haptens

8. The blood group in the ABO system and the resusantigen

A) alloantigens

B) half-haptens

C) proantigens

D) heteroantigens

E) haptens

9. Human tissues are characterized by the absolute individuality of tissue antigens, such antigens refer to

A) half-heptenes

B) alloantigens

C) proantigens

D) to haptens

E) heteroantigens

10. Immunological reaction of a local nature, associated with prolonged exposure to haptens

A) Immunological tolerance

B) Immunological memory

C) secondary response

D) atopy

E) primary response

Lesson№ 16.

1. Topic: Serological reactions.

2. Aim: To master methods of serological diagnosis of infectious diseases.

3. Objectives: Give a description of the types of immunological reactions.

4. Main questions of the topic:

1. Serological and immunological reactions, their practical application in medicine.

2. Groups of serological reactions.

3. The reaction of agglutination.

4. The reaction of indirect, or passive, agglutination (RPA).

5. The reaction of precipitation.

6. Immunodiffusion.

7. Immunoelectrophoresis (IEF).

8. Immunoblotting.

9. Coombs reaction (antiglobulin test).

10. Neutralization and flocculation reactions.

11. The reaction of inhibition of hemagglutination (RTGA).

12. Complement Binding Reaction (RCC).

13. The reaction of immune lysis, hemolysis and immobilization.

14. Opsonophagocytic reaction.

15. Reactions involving labeled antigens or antibodies.

16. Polymerase chain reaction.

5. Methods of learning and teaching: discussion

6. Literature:

1. Medical microbiology, virologists and immunology. Ed. Academician of RAMS Zverev VV, Professor Boychenko MN - Moscow, GEOTAR-Media, 2010. - 1t. - 900 b.

2. Medical microbiology, virology and immunology. Ed. Vorobyeva A.A. - Moscow: MIA, 2008. - 690 p.

3. Medical microbiology, immunology and virology: a textbook for honey. universities. Ed. Korotyaeva AI, Babicheva SA - 5-еизд., Испр.и доп. - SPb .: SpecLit, 2012. - 760 pp. : ill.

4. Medical microbiology, virology, immunology. Ed. Borisova LB ..- M .: MIA, 2006.-734 p.

5. Medical Microbiology / Ch. Ed. Pokrovsky VI, Pozdeev O.K. - Moscow: GEOTAR MEDICINE, 2007.

6. Atlas on medical microbiology, virology and immunology: atlas / ed .: AS Bykov, AA Vorob'ev, VV Zverev. - 2 nd ed., Ext. - M .: Honey. inform. agency, 2008. - 272 p .: ill.

7. A guide to practical exercises on medical microbiology, virology and immunology. Ed. Tetz V.V. -М.: Медицина, 2002.-352 с.

8. Computer program "Diamorph" - "Medical microbiology" - atlas-guidance on bacteriology of mycology, protozoology and virology, edited by acad. prof. Vorobyeva A.A.

9. The determinant of bacteria Berdzhi / Ed. D. Houlta, N. Krig, P. Snitai et al., Moscow: Mir, 1997. - In 2 volumes.

In english language

29. Microbiology Fundamentals: A Clinical Approach - Standalone book 2nd Edition.

30. Richard V Georing, Hazel M Docrell, Mark Zukerman, Derek Wakelin, Ivan M Roit, Cedric Mims, Peter L Chiodini «Medical Microbiology», 4th Edithion, 2008, UK, p.656.

31. Jacquelyn G Black «Microbiology», 7 th ,WILEY, 2010, p. 846.

32. Patric R Muray, Ken S Rosenthal, Michael F Pfaller «Medical Microbiology», 5th Edithion, 2008, p. 962.

Electronic resources:

1. Medicine 3 year [Electrones resource]: a course of lectures. - Electron. text dan. (24.0 MB). - M: Publishing house "Balance", 2005. -1 эл. opt. disk (CD-ROM).

2. Medical microbiology ATLAS - a guide to bacteriology, mycology, protozoology and virology [Electron resource]: for stud. and doctors / ed. A.S. Bykov. -M., 2001. -1 el. opt. disk (CD-ROM).

3. Workshop for laboratory studies on general microbiology [Electron resource]: teaching method. Manual / R.T. Dzhanabaev [et al.] -Sh., 2004. -1 e. opt. disk (CD-ROM).

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