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1. To the urologist the patient N. 22 years old arrived, with complaints about painful urination, purulent discharge from the genital tract. He is sick for about 10 days, the last week he took penicillin. What disease can be suspected? What research methods can you offer? In what case can microscopy give a reliable answer? What material is taken for the study? Why is fast delivery of material to the laboratory important? Why in recent years often have to use bacteriological research? What preventive measures needed dermatological and venereological dispensary appealed to the patient. Objectively: a rash on the body, genitals. The patient leads a disorderly way of life, has many sexual partners. Your preliminary diagnosis. What material will be used for laboratory research? What is the principal scheme of the study, taking into account the patient's lifestyle?
2. A 35-year-old patient complained to the doctor with complaints of pain during urination, the formation of a sore on the genitals. I'm sick for about three weeks. From an anamnesis it is established: two months ago was on a business trip, had sexual relations with unfamiliar women. At inspection it is revealed: on a head of a sexual member an ulcer with sukrovichnymi separated on the dense basis. Palpable inguinal lymphonoduses. A preliminary clinical diagnosis was made: syphilis. With microscopy of the separated ulcer, spirochaetes were not detected. Is this enough to exclude the diagnosis of syphilis? In addition to microscopic examination, Wasserman's reaction with the serum of the patient was used, which gave a positive result. Justify the obtained laboratory data. What other signs are used in medical practice for laboratory diagnosis of syphilis? Justify the usefulness of the bacteriological method for syphilis. The results of Wassermann's reaction, depending on the periods of the disease. HTP, used to treat syphilis.
3. When microscopic examination of the smear from the vagina of the patient A. identified fungi of the genus Candida. Is it possible to make a definitive diagnosis on the basis of this method? Justify the need for additional research.
4. The patient turned to the skin-venereal dispensary with complaints about the appearance of brown spots on the skin. Shortly before treatment, the patient suffered severe pneumonia, received for treatment gentamicin, penicillin and sulfonamide preparations. Microscopy of the smear allowed to make a preliminary diagnosis "Dysbacteriosis, superficial candidiasis". Justify additional research methods to confirm the diagnosis. Justify the appointment of HTP.
Tests:
1. Venereal disease of man, expressed in a purulent lesion of the mucous membranes of the genitourinary system
A) trichomoniasis
B) syphilis
C) venereal granuloma
D) soft chancroid
E) gonorrhea
2. Gram-negative cocci, which propagate the urogenital tract and have the appearance of coffee beans arranged in pairs, concave surfaces to each other are pathogens
A) gonorrhea
B) soft chancre
C) of a venereal granuloma
D) syphilis
E) Trichomoniasis
3. Eukaryotic microorganisms
A) Bacteria
B) mushrooms
C) viruses
D) phages
E) plasmids
4. List the group of lower mushrooms
A) Ascomycetes
B) Basidiomycetes
C) Deuteromycetes
D) Oomycetes
E) Candida
5. The main host of the causative agent of toxoplasmosis
A) dogs
B) rodents
C) rabbits
D) birds
E) cats
6. The causative agent having a large number of cilia
A) balantidium
B) toxoplasm
C) trypanosome
D) amoeba
E) lamblia
7. Mycosis, the first to appear in immunodeficient states
A) favus
B) Candidiasis
C) trichomoniasis
D) Trichophytosis
E) coccidiosis
8. Pathogen having pear-shaped form
A) balantidium
B) amoeba
C) Trichomonas
D) Leishmania
E) trypanosome
9. Pathogen, one of the stages of which has the shape of a crescent
A) trypanosome
B) amoeba
C) toxoplasm
D) Leishmania
E) Trichomonas
10. Disease characterized by inflammation of the urethra and prostate
A) toxoplasmosis
B) amebiasis
C) leishmaniasis
D) trichomoniasis
E) balantidiosis
11 .. Disease, the causative agent of which is transmitted through the tsetse fly bite
A) toxoplasmosis
B) amebiasis
C) leishmaniasis
D) balantidiosis
E) trypanosomiasis
Lesson №8
1.Topic: Zoonotic infections. MBD of zoonotic infections (brucellosis, plague, anthrax, leptospirosis).
Self-study on topics: "Transmissible infections"
2. Aim: Master the microbiological diagnosis of plague, tularemia, brucellosis, anthrax.
3. Objectives: To teach methods of laboratory diagnosis of plague, tularemia, brucellosis, anthrax.
4. Main questions of the topic:
1. Pathogens of especially dangerous infections.
2. Morphology cultural properties of the causative agent of the plague.
3. Biochemical activity and antigenic structure of plague bacteria.
4. Pathogenicity factors of Y. restis.
5. Resistance and epidemiology of the causative agent of the plague.
6. Pathogenesis, clinic and post-infection immunity of the plague.
7. Laboratory diagnosis of plague.
8. Specific prevention and treatment of plague, intradermal allergic test with pestin.
9. Classification, morphology and cultural properties of brucella.
10. Biochemical and antigenic properties of brucella.
11. Resistance and epidemiology of brucellosis.
12. Factors of pathogenicity, pathogenesis and postinfectious immunity of brucellosis.
13. Laboratory diagnosis of brucellosis.
14. Specific prophylaxis and treatment of brucellosis.
15. Morphology and cultural properties of the causative agent of tularemia.
16. Biochemical activity and antigenic structure of tularemia bacillus.
17. Epidemiology and resistance of the causative agent of tularemia.
18. Pathogenicity factors, pathogenesis, clinic and immunity of tularemia.
19. Laboratory diagnosis of tularemia.
20. Treatment and specific prevention of tularemia.
21. Morphology and cultural properties of the causative agent of anthrax.
22. Biochemical and antigenic properties of anthrax bacilli.
23. Resistance and epidemiology of anthrax.
24. Pathogenicity factors, pathogenesis, clinic and immunity of anthrax.
25. Laboratory diagnosis of anthrax.
26. Specific prophylaxis and treatment of anthrax.
27. Morphology and cultural properties of the causative agent of leptospirosis.
28. Biochemical properties, antigenic structure, resistance and epidemiology of the causative agent of leptospirosis.
29. Pathogenicity factors, pathogenesis, clinical features and immunity in leptospirosis.
30. Microbiological diagnosis of leptospirosis.
31. Treatment and specific prevention of leptospirosis.
5. Methods of learning and teaching: discussion
6. Literature:
1. Galaktionov V.T. Immunology. - M. - Ed. "RIC MDK". - 2000. -487
2. Vorobiev A.A. "Microbiology, Immunology" Moscow: MIA, 2002
3. Medical microbiology, virology and immunology. Ed. Vorobyeva A.A. - Moscow: MIA, 2008. - 690 p.
4. Medical microbiology, virology, immunology. Ed. Borisova LB ..- M .: MIA, 2006.-734 p.
5. A.A. Shortanbaev, S.V. Kozhanova "General Immunology", Almaty, 2009
6. R.M. Khaitov "Immunology", Moscow, 2009
7. A. Karaulov "Clinical Immunology and Allergology", Moscow, 2002
Additional:
1. D. Mail, J. Brostoff, D.B. Roit "Immunology", Moscow, 2007
2. N.V. Medunitsyn "Vaccinology", Moscow, 2004
3. D.H. Playfler "Visual Immunology", 2008
4. E. Chepel "Fundamentals of Clinical Immunology", 2008
5. R.M. Khaitov "Clinical Allergology", Moscow, 2002
6. G.B. Fedoseev "Allergology", St. Petersburg, 2001
7. Gordan Ada, Alistair Ramsay "Vaccines, vaccination and immune response", Moscow, 2002
8. S.A. Ketlinsky, A.S. Simbirtsev "Cytokines", St. Petersburg, 2008
9. K.A. Lebedev, I.D. Ponyakina "Immune Deficiency", Moscow, 2003
10. A.A. Totolyan, I.S. Freidlin "Cells of the immune system" I-II, SPb, 2000
11. G.T. Kaliakbarova "Cytokines", Almaty, 2004
12. G.T. Balpanova "Fundamentals of Transplantation Immunity. System HLA », Almaty, 2003
13. B.B. Bizhigitova "The role of the complement system and antigen-presenting cells in the immune response", Almaty, 2006
14. S.G. Mukhambetova, A.S. Karakushikova, Kozhanova SV, Sadvakasova GS "Assessment of the immune status of a person in a clinic", Almaty, 2005
Дата: 2018-12-21, просмотров: 195.